How to Lose a Girl in 10 Days

Losing a girlfriend isn't that challenging. It just takes neglect in a few key areas and a willful arrogance in others. In order to not keep a girl, follow these steps. She'll be gone in no time.

Instructions

1. Step 1

   Forget dates. Stand up the girl whenever possible and be unapologetic when it happens. Keep forgetting plans you have together and never give an explanation. Act suspiciously when she asks where you've been.

2. Step 2

   Stare at other girls. Leave your girlfriend wondering whether you are interested in other girls and whether you may be pursuing them when the two of you are not together.

3. Step 3

   Be thoughtless. Forget that she has feelings and say things that are rude and inappropriate. Tell her that her clothes are unflattering and that her home is dirty.

4. Step 4

   Bring friends along every time you are with your girlfriend. Keep your friends there even when the girl makes it plain that they should leave.

5. Step 5

   Be rude to the girl in front of other people. Make sure her friends and yours hear the things you say to her. Be rude to her friends as well for good measure. Allow her friends to talk her out of dating you.

6. Step 6

   Talk about yourself relentlessly. Interrupt anytime she tries to talk about herself. Talk about how great you are with women, including old girlfriends, and how much they all liked you.

Be the Most Popular College Freshman

Follow these steps and you will become one of the most popular college freshman

After being in high school for four years, college freshman are sometimes uneasy and timid when entering their freshman year of college. This article will show you how to stand out from the crowd, and become well known at your new school. College freshman are usually filled with excitement for a new life, and being out own their own for the first time in your life. Many fail to realize it is very important to do key things that can make your college career the very best experience.

Where you are from

Before we can give you tips, you have to first understand where you are from and what has made you as a person so far in your life. Everything you know has been determined by your parents: Where you live, where you go to school, what friends you have, what your hobbies are... all determined by your parents. Your parents chose where you were to grow up, you made friends within the area that your parents chose to live, your hobbies were determined by activities in the area.

What being a college freshman is

Being a college freshman is your first chance on a level playing field to pick your own friends, do what you want to do, have control over your life to finally mold yourself into who you want to be. With this power comes discipline, because with the ability to change your life for the good, you also have the ability to change it for the bad (ex: dropping out). One of the most important lessons you will learn at college is time management and balance. As much as everyone would love to go out and party all day, you must discipline yourself to get your school work done, or else you days at college could be few and numbered.

Your past and reputation means nothing at college

Everything you have done in your life up until college means absolutely nothing. You will be starting over, you need to work hard to become well known. For some this provides a clean slate to forget some unpleasant things that may of happened in the past. Most likely, other students will only know what you do from that point on (and what you tell them), so try not to disclose anything that may come back and haunt you. (Tip: do not tell anyone past nicknames people called you in high school that you hated) You new job during your freshman year at college is to do the right things to get people to know you, like you, respect you, and make you one of the "popular kids on campus".

How to become popular

There is no guaranteed way to instantly become popular, but there are some guidelines to follow to help get off on the right foot.

• Be Confident - This is very important. No one will know who you are, or how great of a person you are if you spend all your time in your room playing video games or watching TV. The first few weeks of college are very critical, and are most important because people will remember you as you were those first few weeks. You only have one change to make a first impression.
• Meet everyone you can - Say hi to people walking to the cafeteria, introduce yourself, smile be nice. The first few hours after you have moved into your dorm (and your parents finally leave) walk around and introduce yourself to other people, especially on your floor. You will be spending the rest of the year with the people on your floor so you should get to know them as soon as possible. Next meet everyone you can in the rest of your dorm, you may meet their friends in other dorms. The first day of each class introduce yourself to people around you. Chances are you are going to have to work with them in groups or need notes if you miss a class, the first day is the easiest time to do this. Find out when and where the college parties are, and try to go to the best ones, and be friendly to everyone.
• Become involved - Join a student organization, ask around first, see what organizations are cool, what people are involved in. Find something you would enjoy and join a club, organization, fraternity, or sorority. Joining a good active organization, will allow you to meet the more important "active" students on campus.
• Be interested in other people - Don't just ramble on about what you have done, or what you plan to do. Listen to others and ask questions, their lives could be interesting, and you may share something in common.

Unsaid things about boys!

Things Guys Want Girls To Know which otherwise remains unsaid and sometimes becomes difficult for them to bring it out. So here you can get a glimpse over the details that these guys want their girl friends to know which they would otherwise never bother to or be able to tell. So lets get into the minds of these boys and know that always it is not that women are complicated and have lots of secrets in mind rather boys can have a lot of secrets in their mind and be as complex as a girl. This can also prove that boys have so much to tell which these people are not abled to bring out with. They want the girls to know all these facts about them and as they cannot bring with it, they prefer to write it.

The boys are not as perverted as the girls think they are. They are sensible class and they too are not as fool as they are thought to be. Though they seem to be very insensible and stupid at times they are not as they look like. So do not underestimate them as they can be clever enough at times. No matter what girls say, their ex-boyfriend is a loser. And they should never try to prove that their ex boyfriend was really smart enough but it could not be continued as this makes the boys really jealous and angry. So girls be careful from the next time.

The boys like girls to give them hugs and kisses sometimes too, though they will tell they do not want it is always at the back of their mind that they feel happy when they get this kind of responses and be happy with the kisses. So girls remember to keep your boy friends and hubbies happy be ready to give your boys hugs and kisses occasionally though they may not demand for it. Never argue with the boys when they call you beautiful. Because occasionally they would come out with these compliments and never lose the chance. Don't treat boys like crap, what goes around comes around. So try to explain them rather than scolding them.

The boys know that the girls are pretty, that's one of the reason's they are going out with girls. So don't have to always wait for them to give compliments and continue to be nagging and make them angry. Never should a girl go into detail about your period. It scares them. Atleast not before the marriage. After marriage it is alright but not before that. They would never want to know the details of it every month. If girls have cramps and guys ask you what's wrong, just tell these boys it's that time of the month and nothing more.

If the girls really liked these boys as they are then they would let the boys think that their mustache, beard, or sideburns looked cool on them and never complain about it to them. Because they might have replies that would sound harsh. These boys will never shave their legs. So it is better for girls to get over it and be happy with however they are. NEVER ask boys if they can put makeup on their face . It's just wrong on the part of girls to expect such a thing from them. Don't make bets about boys, it is dangerous to prich their ego and make them conscious. When boys tell girls that they are not fat, believe them and never argue with them on these matters as they are right judge of it all. These boys absolutely do not care about the Backstreet Boys, or what any other guy looks like for that matter never pester them to look like someone else and wear clothes like others. They prefer to be themselves.

Whenever the girls are wrong they should apologise to the boys and not just neglect the whole issue as if nothing has happened. The girls expect them to say and do sweet things for them, but it would be nice if you did the same every once in a while. We like to know that you love us and always demand form us. They can't always be spontaneous, so try to help them make the plans. Don't ask the boys to beat up another guy for you, cause you might get what you wish for. Never kick the boys in the nuts just to see what they would say. That really seems nasty. Never pretend that you are going to break up with the boy that you are moving around with . Pamela Anderson's boobs aren't fake anymore, as boys love her and never like her to be criticized but they like their girl friends boobs better anyway.

Size and shape of a girl doesn't matter, except to idiots who don't want a relationship. If the girls want boys to put the seat down when we're done, the girls should put it up when they are done. Don't tell the boys how cute your ex-boyfriend was. That doesn't turn them on rather they get irrigated. And always remember: The way to a guys heart is through his stomach, so take care of his food and start learning to cook as it is easy to keep your man happy only by this method. Never ask boys to kiss other guys. You might be that comfortable with your friends as girls can easily do that, but to them it's just wrong. The boys know that the girls are not always right, but we'll pretend like you are anyway okay and try to neglect the matter so always take care of the issues as the boys try to be very patient and considerate enough so never try their patience.

What should you do to win a girl's heart?

Answer

Most girls worth anything like a guy that listens to them and realizes they have a brain

Don't be afraid to express what you want in the future and be sure to ask what she wants

Don't tell her everything about yourself because women like a man with a bit of mystery to him and vice-versa

Treat her with respect and if she doesn't treat you the same way let her know right then and there you aren't putting up with it. Women like men that can stand on their own two feet. Even though women act independent and many are, they always fall back on the fact they want to know they can lean on their guy when they need to.

Be a gentleman without hanging all over her.

Be proud to show her off to family and friends

If she earns it, then always speak highly of her

If you think she's pretty/cute then say so and that goes for any other compliments you may have for her.

Make any dates with her earlier in the week. Take her to movies, clubs, etc. Do what you can afford. Sometimes it's just nice to grab some roasted peanuts from a vender and go for a romantic walk along a beautiful beach or by a lake.

Never forget to always act yourself and never try to be someone you aren't.

Good luck Marcy

Answer

Buy her things.

Also, allow her to love herself through your eyes. Make her feel cool and smart.

Answer

Be yourself, thats the only way to win her heart. If its meant to be it will be.

H5N1 pandemic flu vaccine developed by Glaxo SmithKline successful

GlaxoSmithKline (GSK) plc today announced headline data showing that its H5N1 pandemic flu vaccine achieved a high immune response at a low dose of antigen. The vaccine, which uses a proprietary adjuvant, enabled over 80% of subjects who received 3.8�g of antigen to demonstrate a strong seroprotective immune response.

This level of seroprotection meets or exceeds target criteria set by regulatory agencies for registration of influenza vaccines. Efficacy results at these levels of antigen dosage have also not been reported for any other H5N1 vaccine in development to date, including those using other adjuvants such as alum.

Commenting on the data, JP Garnier, GlaxoSmithKline�s Chief Executive Officer, said: �These excellent clinical trial results represent a significant breakthrough in the development of our pandemic flu vaccine. This is the first time such a low dose of H5N1 antigen has been able to stimulate this level of strong immune response.

There is still a lot more work to be done with this programme, but this validation of our approach provides us with the confidence to continue developing the vaccine, including assessment of its ability to offer cross-protection to variants of the H5N1 strain. All being well, we expect to make regulatory filings for the vaccine in the coming months.�

The results were based on an interim analysis of a clinical trial conducted in Belgium which involved 400 healthy adults aged 18-60 years of age. The vaccine tested was produced from inactivated H5N1 virus and contained a novel, proprietary adjuvant. An adjuvant is an ingredient which stimulates the immune system and increases response to the vaccine. Trial participants were vaccinated twice during the course of the trial and four different levels of antigen dose were tested, with 3.8�g being the lowest dose assessed.

The impact of smoking and genes on rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the most common systemic autoimmune diseases, and one of the least understood. Smoking is the major known environmental risk factor for RA, though little is known about the mechanisms involved. HLA-DR shared epitope (SE) genes are a widely recognized genetic risk factor for RA, though little is known about how these genes affect autoimmune reactions that lead to chronic inflammation and progressive joint and organ damage.

To better understand the interactions between smoking and HLA-DR SE genes in RA, a team of researchers in Sweden focused on the disease's distinctive autoimmune hallmark: citrulline, an amino acid not normally present in protein. While extremely rare in healthy individuals and relatively rare in other inflammatory conditions, citrulline-modified proteins are common in about two-thirds of RA patients and may be an underlying factor in the development of the disease. To investigate whether smoking and SE genes trigger immune reactions to citrullinated proteins, the team conducted a case-control study involving patients with recent-onset RA. The results, featured in the January 2006 issue of Arthritis & Rheumatism, suggest that smokers with SE genes are more susceptible to anticitrulline antibody-positive RA.

The study's 930 early RA patients, drawn from the Epidemiological Investigation of Rheumatoid Arthritis Study Group, ranged in age from 18 to 70 years. 383 healthy controls, drawn from the blood bank of northern Sweden, were matched for age, gender, and residential area. All participants completed questionnaires about their past and present smoking habits, as well as genotyping profiles. In addition, bronchial fluid was obtained from a representative sample of RA patients, including both current heavy smokers and lifelong non-smokers, and tested with immunostaining for the presence of citrullinated protein in cells.

Tobacco smoking

Tobacco smoking is the practice where tobacco is burned and the vapors either tasted or inhaled. The practice began as early as 5000–3000 BC.^[1] Many civilizations burnt incense during religious rituals, which was later adopted for pleasure or as a social tool.^[2] Tobacco was introduced to the old world in the late 1500s where it followed common trade routes. The substance was met with frequent criticism, but became popular nonetheless.^[3] German scientists formally identified the link between smoking and lung cancer in the late 1920s leading the first anti-smoking campaign in modern history. The movement, however, failed to reach across enemy lines during the Second World War, and quickly became unpopular thereafter.^[4] In 1950, health authorities again began to suggest a relationship between smoking and cancer.^[5] Scientific evidence mounted in the 1980s, which prompted political action against the practice. Rates of consumption from 1965 onward in the developed world have either peaked or declined.^[6] They however continue to climb in the developing world.^[7]

Smoking is the most common method of consuming tobacco, and tobacco is the most common substance smoked. The agricultural product is often mixed with other additives^[8] and then pyrolyzed. The resulting vapors are then inhaled and the active substances absorbed through the alveoli in the lungs.^[9] The active substances trigger chemical reactions in nerve endings which hightens heart rate, memory, alertness,^[10] and reaction time.^[11] Dopamine and later endorphins are released, which are often associated with reward and pleasure.^[12] As of 2000, smoking is practiced by some 1.22 billion people. Men are more likely to smoke than women,^[13] however the gender gap declines with younger age.^[14][15] The poor are more likely to smoke than the wealthy, and people of developing countries than those of developed countries.^[7]

Many smokers begin during adolescence or early adulthood. During the early stages, smoking provides pleasurable sensations and thus serves as a source of positive reinforcement. After an individual has smoked for many years, the avoidance of withdrawal symptoms and negative reinforcement become the key motivations.